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switchSENSE® TECH DAYS

Dynamic Biosensors GmbH

Tuesday, May 7, 2019 from 10:00 AM to 4:00 PM (CEST)

switchSENSE® TECH DAYS
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Event Details

switchSENSE® TECH DAYS –
BIOSENSING WITH ELECTRO-SWITCHABLE BIOSURFACES

switchSENSE® is an automated biosensor chip technology that employs electrically actuated DNA nanolevers for the real-time measurement of binding kinetics (kON, kOFF) and affinities (KD).
Interactions between proteins, DNA/RNA, and small molecules can be detected with high sensitivity. Application examples of protein – protein, small molecule – DNA, sizing and conformational changes will be presented.


PROGRAM
SCIENTIFIC TALKS  I  TECHNICAL TUTORIALS  I  HANDS-ON EXPERIMENTS

Tuesday, May 07th
PROTEIN-DNA INTERACTIONS

Aptamers | Powerful tool for fast and easy diagnostics

10:00am 
switchSENSE® scientific presentation 

11:00am 
Hands-on switchSENSE® experiments: 
Real-time investigation of thrombin interaction with DNA aptamers


Wednesday, May 08th
PROTEIN-SMALL MOLECULES INTERACTIONS

Small Molecules |
Go beyond KD determination in drug discovery process

10:00am 
switchSENSE® scientific presentation 

11:00am 
Hands-on switchSENSE® experiments: 
Protein interaction with small molecules using electrically actuated  DNA nanolevers


Thursday, May 09th
ANTIGEN-ANTIBODY INTERACTIONS

Antibodies | Where off-rates matter

10:00am 
switchSENSE® scientific presentation 

11:00am 
Hands-on switchSENSE® experiments: 
Characterization of antibody interactions and hydrodynamic sizing



switchSENSE® technology delivers unrivaled information on a single platform 

dynamicBIOSENSORS’ pioneering switchSENSE® sensor platform is an automated, fluorescence based biosensor chip technology that employs electrically actuated DNA nanolevers for the real-time measurement of binding kinetics (kON, kOFF) and affinities (with KD values down to the fM range). The platform offers an automated ligand density control, which allows to conveniently discriminate between affinity and avidity in one single assay. Interactions between proteins, DNA/RNA, and small molecules can be detected with femto-molar sensitivity. Using minimal amounts of sample, protein diameters (DH) and conformational changes are analyzed with 0.1 nm accuracy, as well as protein melting transitions (TM).
As a world’s first, our double color DRX² analyzer enables the simultaneous measurement of two different species of probes on the same detection spot. This offers the possibility of on-spot referencing or dual binding modelling, which is ideal for bispecific and proof-of-action experiments.

Have questions about switchSENSE® TECH DAYS? Contact Dynamic Biosensors GmbH

When & Where


Pro-Environment Polska Sp. z o.o.
Ul. Żwirki i Wigury 101
02-089 Warszawa
Poland

Tuesday, May 7, 2019 from 10:00 AM to 4:00 PM (CEST)


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Organizer

Dynamic Biosensors GmbH

DYNAMIC BIOSENSORS - ANALYZING MOLECULES IN MOTION

dynamicBIOSENSORS is a provider of instruments, consumables, and services in the field of analytical systems for the characterization of biomolecules and molecular interactions. We are located in Martinsried, south of Munich, a vital center of Europe‘s biotechnology industry. 

dynamicBIOSENSORS commercializes switchSENSE® technology, a groundbreaking platform technology for the analysis of biomolecules with applications in R&D and drug development.

The switchSENSE® technology is protected worldwide and only available through dynamicBIOSENSORS. The company is headquartered in the south of Munich, Germany and runs offices in the United States, the United Kingdom, Japan and Singapore.

www.dynamic-biosensors.com 

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